Consider cephalosporins like cefuroxime or ceftriaxone for respiratory or urinary tract infections if amoxicillin proves ineffective or causes adverse reactions. These offer broader coverage than amoxicillin.
For skin infections, clindamycin may be a suitable alternative. It’s generally well-tolerated by the elderly, but monitor for diarrhea.
Respiratory infections unresponsive to amoxicillin might benefit from macrolides like azithromycin or clarithromycin. These are generally better tolerated than some other alternatives but carry a higher risk of QT prolongation; electrocardiogram (ECG) monitoring may be necessary for patients with risk factors.
In cases of severe infections or antibiotic resistance, consider a fluoroquinolone like levofloxacin or moxifloxacin. However, these should be reserved for serious infections due to potential side effects, especially tendon damage and potential for C. difficile colitis.
Always consult prescribing information and consider individual patient factors, including existing conditions, allergies, and drug interactions, before choosing an antibiotic.
Regularly monitor patients for treatment efficacy and side effects. Adjust dosage based on renal function as indicated in the product literature. This is especially vital with elderly patients who may have reduced kidney function.
