Cardizem (diltiazem), administered intravenously, slows the heart rate and reduces the force of contractions in atrial fibrillation (Afib). This dual action is key to its effectiveness.
Specifically, Cardizem blocks calcium channels in cardiac muscle cells. This slows the conduction of electrical impulses through the heart, reducing the rapid and irregular heartbeats characteristic of Afib. Lowering the heart rate helps control symptoms like palpitations and shortness of breath.
Impact on Atrial Fibrillation
By decreasing the atrial rate, Cardizem helps improve ventricular response. This means the ventricles (lower chambers of the heart) don’t beat as rapidly and erratically. This is beneficial in preventing complications associated with rapid ventricular rates, such as shortness of breath, chest pain, and heart failure.
Dosage and Monitoring
Dosage is carefully adjusted based on the patient’s response and heart rate. Continuous monitoring is crucial to observe for side effects, such as hypotension and bradycardia (slow heart rate). This allows for timely adjustments to maintain a safe and effective heart rate.
Potential Side Effects & Interactions
While Cardizem is generally safe and effective, potential side effects include nausea, dizziness, and headache. It’s important to be aware of potential drug interactions, especially with other medications that affect heart rate or blood pressure. Always consult with a healthcare professional.
| Hypotension | Low blood pressure | Reduce infusion rate or temporarily halt infusion. |
| Bradycardia | Slow heart rate | Reduce infusion rate or temporarily halt infusion; consider atropine. |
| Nausea | Feeling sick to stomach | Antiemetic medication may be considered. |
Alternative Considerations
Cardizem isn’t always the first-line treatment for Afib. Other medications, such as beta-blockers, are often used. The choice of medication depends on the individual patient’s condition and other health factors. A healthcare professional will determine the most appropriate treatment strategy.
