Alternatives to Doxycycline for UTI Treatment

For uncomplicated UTIs, your doctor might prescribe nitrofurantoin (Macrobid or Macrodantin). This antibiotic targets bacteria specifically in the urinary tract, minimizing impact on your gut microbiome. It’s generally well-tolerated, but can cause nausea or stomach upset in some.

Another common choice is trimethoprim-sulfamethoxazole (Bactrim or Septra). This combination antibiotic is effective against a wide range of UTI-causing bacteria. However, increasing bacterial resistance is a concern, so your doctor will consider your medical history and local resistance patterns.

Fosfomycin (Monurol) is a single-dose antibiotic often used for uncomplicated UTIs. Its convenience is appealing to many patients. However, it may not be suitable for recurrent infections.

Cephalexin (Keflex) is a cephalosporin antibiotic that can treat UTIs, especially those caused by *E. coli*. It’s typically prescribed for more severe or complicated cases, or when other antibiotics haven’t been effective.

Always discuss your treatment options with your doctor. They will consider factors like your medical history, allergy history, and the specific bacteria causing your UTI to recommend the most appropriate antibiotic for your situation. Never self-treat a UTI; early diagnosis and proper treatment are vital for preventing complications.