Viagra (sildenafil) primarily works by inhibiting an enzyme called phosphodiesterase-5 (PDE5). This inhibition increases levels of cyclic guanosine monophosphate (cGMP), a molecule that relaxes blood vessels in the penis, leading to improved blood flow and facilitating an erection.
However, this same mechanism can affect blood vessels throughout the body. Because Viagra dilates blood vessels, it can lower blood pressure. This effect is generally mild in healthy individuals, but it poses potential risks for those with pre-existing cardiovascular conditions.
- Nitrates: A significant interaction exists between Viagra and nitrates (often prescribed for angina). Combining them can cause a dangerously sharp drop in blood pressure. This combination is strictly contraindicated. Heart disease: Men with unstable angina, severe heart failure, or uncontrolled high blood pressure should avoid Viagra. The drug’s vasodilatory effects could exacerbate these conditions. Recent heart attack or stroke: Using Viagra within the first few months after a heart attack or stroke carries increased risks due to the potential strain on the cardiovascular system.
Consult your physician before using Viagra, especially if you have a history of heart problems or are taking other medications. They can assess your individual risk factors and determine if Viagra is safe for you. A thorough medical evaluation is always recommended.
Openly discuss your medical history with your doctor, including all medications you’re taking. Undergo any necessary cardiac assessments to gauge your heart’s health. Follow your physician’s advice diligently regarding Viagra usage.
Remember, this information is not a substitute for professional medical advice. Always seek the guidance of your doctor or other qualified healthcare provider for any questions regarding your health and treatment options.
