Vytorin 10/20 contains two active ingredients: 10 mg of simvastatin and 20 mg of ezetimibe. Simvastatin is a statin, lowering cholesterol production in the liver. Ezetimibe works differently, blocking cholesterol absorption in the intestines. This combination approach targets cholesterol reduction from both sources.
Simvastatin’s Role
Simvastatin inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis. This leads to a decrease in LDL (“bad”) cholesterol and an increase in HDL (“good”) cholesterol levels. It’s crucial to understand that simvastatin’s effectiveness varies depending on individual factors.
Ezetimibe’s Contribution
Ezetimibe selectively inhibits cholesterol absorption in the small intestine. By reducing the amount of cholesterol absorbed from food, it further contributes to lowering LDL cholesterol. Combining it with simvastatin enhances the overall cholesterol-lowering effect.
Note: Always consult your doctor before starting or changing any medication, including Vytorin. They can assess your individual needs and risks associated with this combination therapy.
