First, accurately weigh your promethazine base. Use a calibrated scale for precise measurement. This ensures consistent potency in your final product.
Next, carefully measure the required amount of your chosen gel base. Common bases include carbomer 940 or hyaluronic acid. Follow the specific instructions for your selected base regarding hydration and mixing.
Gradually incorporate the promethazine into the gel base. Stir gently but thoroughly to prevent clumping and ensure uniform distribution. Avoid vigorous mixing, which could introduce air bubbles.
Once fully mixed, assess the consistency of your gel. Adjust the amount of base if necessary to achieve the desired viscosity. Thicker bases create firmer gels.
Finally, transfer the prepared promethazine gel into a suitable, sterile container. Label the container with the contents, concentration, and preparation date for easy identification and tracking.


