Always inform your doctor about all medications you’re taking, including over-the-counter drugs, herbal supplements, and recreational drugs, before starting Sildenafil. Certain combinations can be dangerous.
Nitrates are strictly contraindicated. Combining Sildenafil with nitrates (found in some heart medications) can cause a dangerously low blood pressure.
Alpha-blockers, often used to treat high blood pressure or enlarged prostate, may cause dizziness or lightheadedness when taken with Sildenafil. Your doctor may adjust your dosages.
CYP3A4 inhibitors, such as ketoconazole and ritonavir, increase Sildenafil levels in the blood, potentially leading to side effects. Your doctor might recommend a lower Sildenafil dose.
Conversely, CYP3A4 inducers, like rifampicin, can decrease Sildenafil effectiveness. This interaction needs careful monitoring by your physician.
Combining Sildenafil with other PDE5 inhibitors is inadvisable. Using multiple drugs in this class simultaneously increases the risk of side effects.
Grapefruit juice inhibits the metabolism of Sildenafil, potentially raising its blood levels. Limit or avoid grapefruit juice while taking Sildenafil.
Alcohol can intensify Sildenafil’s side effects, particularly dizziness and hypotension. Moderate your alcohol intake while on this medication.
This information is not exhaustive. Consult your physician or pharmacist for personalized advice regarding potential drug interactions with Sildenafil 20mg.
