Avoid Vardenafil trihydrate hydrochloride 20 mg with nitrates (like nitroglycerin) due to a significant risk of dangerously low blood pressure. This combination can cause dizziness, fainting, and even heart attack.
Alpha-Blockers and Vardenafil
Using Vardenafil with alpha-blockers (used to treat high blood pressure or enlarged prostate) significantly increases the chance of low blood pressure. Monitor your blood pressure closely and report any significant drops to your doctor immediately.
Other Medications Requiring Caution:
- CYP3A4 Inhibitors: Medications that inhibit the CYP3A4 enzyme (like ketoconazole, erythromycin, and grapefruit juice) can increase Vardenafil levels, leading to increased side effects. Discuss these medications with your doctor before taking Vardenafil. CYP3A4 Inducers: Conversely, medications that induce CYP3A4 (like rifampicin) can decrease Vardenafil levels, reducing its effectiveness. Your doctor may need to adjust your dosage. Other Erectile Dysfunction Medications: Combining Vardenafil with other phosphodiesterase-5 (PDE5) inhibitors (like sildenafil or tadalafil) is dangerous and should be strictly avoided.
Specific Recommendations:
Provide your doctor with a complete list of all medications, supplements, and herbal remedies you are currently taking. Do not self-medicate. Always consult your doctor or pharmacist before starting or stopping any medication. Inform your healthcare provider about any health conditions you have, especially heart problems, liver or kidney disease.
Alcohol Consumption:
Limit alcohol consumption while taking Vardenafil, as combining the two can intensify side effects like dizziness and headaches.