Imuran (azathioprine) is prescribed for lupus nephritis, specifically when the disease affects your kidneys. This typically means your doctor has seen evidence of kidney damage in blood tests or imaging scans showing lupus-related inflammation affecting your kidneys. The specific indication relies on the severity and activity of the nephritis.

Severe Lupus Nephritis

Doctors often prescribe Imuran for severe lupus nephritis, characterized by significant protein in the urine (proteinuria), high blood pressure, or reduced kidney function. This is a more aggressive approach to manage the condition and prevent further kidney damage.

Lupus-Related Symptoms Resistant to Other Treatments

If other treatments like corticosteroids haven’t adequately controlled your lupus symptoms or if you experience significant side effects from corticosteroids, your doctor might add Imuran to your treatment plan to help reduce inflammation and control disease activity. This might include symptoms like severe joint pain, skin rashes, or fatigue.

Preventing Relapses

Once your lupus is under control, Imuran can be used to help maintain remission and lower the chance of future flare-ups. This preventative use is frequently combined with other medications to create a robust treatment strategy.