Roxithromycin is a macrolide antibiotic. It fights bacterial infections by preventing bacteria from producing proteins they need to survive and reproduce. Specifically, it binds to the 50S ribosomal subunit, halting protein synthesis.
Mechanism of Action
This binding action is highly selective for bacterial ribosomes, minimizing harm to human cells. This selective targeting is key to its effectiveness. Roxithromycin’s broad spectrum covers a range of bacteria, including Streptococcus pneumoniae, Haemophilus influenzae, and Mycoplasma pneumoniae, commonly causing respiratory infections. It also works against some atypical bacteria and certain gram-positive organisms.
Pharmacokinetics
Roxithromycin is well-absorbed after oral administration, achieving therapeutic concentrations in various tissues. It’s metabolized in the liver, and excreted primarily via the bile. This metabolic process leads to prolonged activity, often allowing for once-daily dosing.
Important Note:
Always consult a doctor before taking any medication, including roxithromycin. Incorrect usage can lead to antibiotic resistance. This information is for educational purposes only and does not constitute medical advice.
