Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain and inflammation. It’s prescribed to treat osteoarthritis and rheumatoid arthritis.
Unlike many other NSAIDs, nabumetone doesn’t directly inhibit cyclooxygenase (COX) enzymes. Instead, it’s a prodrug, meaning your body converts it into active metabolites that then affect COX enzymes.
- This conversion process occurs primarily in the liver. The active metabolites reduce pain and inflammation by blocking the production of prostaglandins.
Nabumetone is available in tablet form and typically taken once or twice daily, depending on your doctor’s instructions. Dosage varies based on individual needs and health conditions.
Always follow your doctor’s prescription carefully. Never exceed the recommended dosage. Report any side effects to your doctor promptly.
Common side effects can include stomach upset, nausea, and heartburn. More serious, though less frequent, side effects include kidney problems, liver damage, and increased risk of cardiovascular events. Discuss potential risks and benefits with your doctor before starting treatment.
Nabumetone isn’t suitable for everyone. Those with a history of ulcers, heart conditions, or kidney problems should exercise particular caution and consult their physician.
