Celebrex (celecoxib) is a nonsteroidal anti-inflammatory drug (NSAID), specifically a COX-2 inhibitor. It targets cyclooxygenase-2 (COX-2), an enzyme involved in pain and inflammation.
How Celebrex Reduces Pain and Inflammation
Unlike older NSAIDs that block both COX-1 and COX-2 enzymes, Celebrex selectively inhibits COX-2. This reduces inflammation and pain without significantly affecting COX-1, which protects the stomach lining. This selective inhibition is why Celebrex generally causes fewer gastrointestinal side effects than older NSAIDs.
Celebrex and Osteoarthritis
In osteoarthritis, cartilage breakdown causes pain and inflammation. Celecoxib reduces this inflammation, providing pain relief and improving joint function. Always follow your doctor’s prescribed dosage and instructions for use. Discuss potential risks and benefits with your physician.
Important Considerations
Note: Celebrex is not suitable for everyone. Individuals with certain medical conditions, such as a history of heart disease, stroke, or severe kidney or liver problems, should consult their doctor before taking Celebrex. Possible side effects include increased risk of heart attack or stroke, fluid retention, and high blood pressure. Always consult your healthcare provider for personalized advice.
