What is Brimonidine and How Does it Work?

Brimonidine is an alpha-2 adrenergic agonist. It works by constricting blood vessels in the skin, reducing redness and swelling. This action makes it effective for treating rosacea, a skin condition characterized by facial redness and inflammation.

Mechanism of Action

Specifically, brimonidine binds to alpha-2 adrenergic receptors on the surface of blood vessel cells. This binding triggers a cascade of intracellular events leading to reduced blood flow in the treated area. The result is a visible decrease in redness. This effect is generally temporary, lasting several hours.

The cream’s efficacy varies depending on individual factors and the severity of rosacea. Patients should always consult their dermatologist for personalized advice and to discuss potential side effects.