Viagra, or sildenafil, primarily lowers blood pressure by inhibiting an enzyme called phosphodiesterase-5 (PDE5). This enzyme normally breaks down cyclic guanosine monophosphate (cGMP), a molecule that relaxes blood vessels. By blocking PDE5, Viagra increases cGMP levels, leading to vasodilation – widening of blood vessels.
This vasodilation affects multiple blood vessels, including those in the lungs and the penis. In the context of high blood pressure, this effect can be either beneficial or detrimental, depending on factors like the individual’s overall health, current medications, and the dose of Viagra.
The reduction in blood pressure is usually mild to moderate. However, it’s important to note that Viagra can interact negatively with nitrates, a class of medications often used to treat angina (chest pain). This combination can cause a dangerous drop in blood pressure. Individuals taking nitrates should absolutely avoid Viagra.
For those with hypertension already managed by medication, combining Viagra with blood pressure drugs may cause an excessive drop in blood pressure, leading to dizziness, fainting, or other adverse effects. Careful monitoring and consultation with a physician are crucial before using Viagra if you have high blood pressure or take blood pressure medication.
Always consult your doctor before starting Viagra, especially if you have pre-existing health conditions, including high blood pressure. They can help assess your individual risk and determine the appropriate course of action.
