Cialis treats erectile dysfunction by inhibiting phosphodiesterase type 5 (PDE5). This enzyme usually breaks down cyclic guanosine monophosphate (cGMP), a crucial molecule for achieving and maintaining an erection. By blocking PDE5, Cialis allows cGMP levels to rise. Increased cGMP relaxes the smooth muscles in the penis, boosting blood flow and facilitating erection.
Specifically, nitric oxide (NO) triggers the production of cGMP. Cialis enhances the effect of NO, thereby amplifying the cGMP increase and leading to a stronger and more sustained erection. The duration of Cialis’s effect, often lasting up to 36 hours, stems from its longer half-life compared to other PDE5 inhibitors.
Remember, Cialis doesn’t directly cause an erection; it enhances the body’s natural response to sexual stimulation. Sexual stimulation is still necessary to trigger the release of NO and initiate the erection process. Cialis simply optimizes this process.
This mechanism explains why Cialis is effective for many men with erectile dysfunction. However, individual responses can vary, and underlying medical conditions may influence its efficacy. Consult your doctor to discuss Cialis and determine its suitability for your specific situation.
