Always inform your doctor about all medications you take, including over-the-counter drugs, supplements, and herbal remedies. Tadalafil can interact negatively with nitrates, commonly used to treat angina (chest pain). This combination can cause a dangerous drop in blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Tadalafil; it can increase Tadalafil levels in your blood, potentially leading to side effects.
Specific Medication Interactions
Certain medications, such as alpha-blockers (used for high blood pressure or prostate problems), antifungals like ketoconazole and itraconazole, and HIV protease inhibitors, may increase Tadalafil’s effects or side effects. Your doctor should carefully assess the risks and benefits of combining Tadalafil with these drugs. Similarly, rifampin, a medication used to treat tuberculosis, can decrease Tadalafil’s effectiveness. Open communication with your healthcare provider is crucial.
Contraindications
Men with certain heart conditions, particularly those who have experienced a recent heart attack, stroke, or unstable angina, should not use Tadalafil. Individuals with uncontrolled high blood pressure or low blood pressure should also avoid using it. Tadalafil is contraindicated for people with severe liver or kidney problems, as well as those with a history of non-arteritic anterior ischemic optic neuropathy (NAION), a type of vision loss. If you have retinitis pigmentosa (a rare inherited eye disease), using Tadalafil carries additional risks. Consult your doctor before taking Tadalafil if you have any pre-existing medical conditions.
