Avoid combining phenylephrine and acetaminophen with monoamine oxidase inhibitors (MAOIs) due to potential for dangerously high blood pressure. Consult your doctor before use if you have heart disease, high blood pressure, thyroid problems, or diabetes. Phenylephrine can exacerbate these conditions.
Pregnancy and Breastfeeding
Pregnant or breastfeeding individuals should consult a healthcare provider before using either medication. Phenylephrine may constrict blood vessels, potentially affecting placental blood flow. Acetaminophen generally is considered safe during pregnancy, but always consult your doctor before taking any medication during pregnancy or while breastfeeding.
Interactions with Other Medications
Inform your doctor or pharmacist about all medications, including over-the-counter drugs and herbal supplements, you are currently taking. Certain medications can interact with phenylephrine or acetaminophen, leading to adverse effects. This includes medications for high blood pressure, antidepressants, and other decongestants.
Allergic Reactions
Stop using the medication and seek immediate medical attention if you experience allergic reactions, such as hives, difficulty breathing, swelling of the face, lips, tongue, or throat. These are serious and require prompt medical care.
