Accurately calculate the dose based on the patient’s body surface area (BSA) in square meters (m²). Use a reliable BSA calculator, ensuring accurate height and weight measurements.
For example, a patient with a BSA of 1.7 m² requires 1.7 m² * 50 mg/m² = 85 mg of methotrexate.
Administer the calculated dose as directed by a healthcare professional. Common routes include intravenous (IV) push or infusion, or intramuscular (IM) injection. Never administer without proper training and supervision. Always follow established hospital protocols.
Dosage frequency varies depending on the treatment indication. Consult the prescribing information for specific recommendations for the condition being treated. Regular monitoring of blood counts is necessary.
| BSA Calculation | Use a validated formula; ensure accuracy of measurements. |
| Dosage Adjustment | Renal and hepatic function should influence dose adjustments. |
| Administration Route | IV, IM; follow guidelines and protocols. |
| Monitoring | Closely monitor complete blood count and liver function tests. |
| Adverse Effects | Be aware of potential side effects, such as mucositis, nausea, and myelosuppression. Report any concerning symptoms immediately. |
Always refer to the most up-to-date prescribing information for complete details on dosage, administration, and adverse effects. This information is for educational purposes only and should not be considered medical advice.
