Always inform your doctor about all medications you take, including over-the-counter drugs, supplements, and herbal remedies. This is crucial for preventing dangerous interactions.
Lamictal (lamotrigine) interacts with several medications. Some increase Lamictal levels in your blood, potentially leading to serious side effects. Others decrease Lamictal’s effectiveness.
| Oral contraceptives | Many brands | May decrease Lamictal levels; dosage adjustments may be needed. |
| Valproic acid (Depakote) | Depakene, Depakote | Significantly increases Lamictal levels; requires careful monitoring and potentially lower Lamictal dosage. |
| Rifampin | Rifadin, Rimactane | Decreases Lamictal levels; requires higher Lamictal dosage. |
| Strong CYP2C19 inhibitors | Omeprazole, fluoxetine | May increase Lamictal levels; requires monitoring. |
| Strong CYP3A4 inducers | St. John’s Wort, Carbamazepine | May decrease Lamictal levels; requires higher Lamictine dosage. |
This table provides examples; it is not exhaustive. Always consult your physician or pharmacist for a complete list of potential interactions and appropriate dosage adjustments. Regular blood tests may be necessary to monitor Lamictal levels and ensure your safety and treatment efficacy.
