Flucloxacillin dosage depends heavily on the infection’s severity and the patient’s age and renal function. Always refer to your prescribing information for precise guidance.
Adults typically receive 250-500mg every four to six hours. Severe infections may warrant higher doses, up to 1g every four hours.
- Children’s dosages are weight-based and significantly lower. Adjustments are frequently needed for patients with kidney problems.
Administer flucloxacillin orally, with or without food. Intravenous administration is an option for severe infections or when oral intake is impossible. For intravenous administration, follow dilution and infusion rate instructions meticulously. Incorrect administration can lead to thrombophlebitis.
Regularly monitor for signs of allergic reactions, including skin rashes, itching, and swelling. Stop administration immediately if an allergic reaction occurs. Closely observe for signs of liver or kidney problems. Liver function tests and creatinine levels provide valuable insights. Assess clinical response to treatment. Improvement should be visible within a few days. If no improvement is seen, reassess the diagnosis and consider alternative treatment options. Monitor for Clostridium difficile-associated diarrhea (CDAD), a potential side effect. This requires prompt medical attention.
Remember, accurate dosage, proper administration, and consistent monitoring are paramount for successful treatment and minimizing potential adverse effects. Patient education is key to ensure compliance and early detection of complications. Always consult relevant prescribing information for your region.


